CUSTOM SYNTHESIS
[Synthesis with subsequent process scale-up]
Although our main focus is developing large-scale industrial processes, our modern laboratory also enables us to efficiently fulfil orders for the synthesis of small quantities of compounds.
Unique solutions
Our clients often need to assess the potential of a business idea or replace a key component. If a project goes beyond producing a sample and envisages launching production in Russia, synthesis at our engineering centre is a sound choice. We use rational, cost-effective approaches to minimise costs and prepare the process for subsequent scale-up.
Comprehensive consulting on project-specific challenges beyond the original scope of work
Synthesis of compounds with strict requirements for trace impurities and physical properties, including for biotechnology and microelectronics
In-house fabrication of custom reactors for demanding conditions (ultrapure substances, oxygen-free and anhydrous environments, vacuum distillation down to 10-3 mbar, and more)
Initial validation samples within a few days
Flexible filling, packaging and shipping options
Synthesis at pressures up to 300 atm
Synthesis in continuous-flow systems using heterogeneous catalysis
Methods and equipment beyond conventional organic synthesis
Key
synthetic methods
(RAFT — reversible addition–fragmentation chain-transfer polymerisation; ATRP — atom transfer radical polymerisation)
Synthesis of complex copolymers
Chemical modification of polymers
Synthesis of heterocyclic compounds
Alkylation and acylation of aromatic compounds, alcohols and amines
Stereoselective synthesis
Polymerisation reactions of various types, including highly selective polymerisation
Selective carbon-skeleton construction (Grignard, Wittig, Suzuki and Heck reactions, among others)
Hydrogenation with metal hydrides and heterogeneous catalytic hydrogenation with gaseous hydrogen
Syntheses using phase-transfer catalysis
Condensation of carbonyl compounds
Oxidation and reduction of organic compounds
Electrophilic aromatic substitution (acylation, nitration, bromination, sulfonation and others)
Synthesis of esters
Electrophilic and radical halogenation
Classes of compounds we work with
Substituted aromatic compounds
Carboxylic acids and their anhydrides
Aldehydes and ketones
Esters and ethers
Heterocyclic compounds
Amines
Alcohols
[6]
[4]
Halogenated compounds
Organophosphorus and organosulfur compounds
[12]
[11]
[9]
[10]
Polymeric compounds
Organometallic compounds
[8]
[7]
[5]
[3]
[2]
[1]
Hydrocarbons